Neuronal and glial alterations, increased anxiety, and cognitive impairment before hippocampal amyloid deposition in PDAPP mice, model of Alzheimer's disease

Author:

Beauquis Juan1,Vinuesa Angeles1,Pomilio Carlos1,Pavía Patricio1,Galván Verónica2,Saravia Flavia1

Affiliation:

1. Instituto de Biología y Medicina Experimental CONICET and Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales; Universidad de Buenos Aires; Argentina

2. Department of Physiology and The Barshop Institute for Longevity and Aging Studies; University of Texas Health Science Center at San Antonio; Texas

Publisher

Wiley

Subject

Cognitive Neuroscience

Reference53 articles.

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2. Changes in cognition;Albert;Neurobiol Aging 32 (Suppl,2011

3. Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition;Arendash;Neuroreport,2004

4. Anatomical brain images alone can accurately diagnose chronic neuropsychiatric illnesses;Bansal;PLoS One,2012

5. When is the hippocampus involved in recognition memory?;Barker;J Neurosci,2011

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