An Inverse Agonist Ligand of the PTH Receptor Partially Rescues Skeletal Defects in a Mouse Model of Jansen's Metaphyseal Chondrodysplasia-Reference-Cited by-同舟云学术

An Inverse Agonist Ligand of the PTH Receptor Partially Rescues Skeletal Defects in a Mouse Model of Jansen's Metaphyseal Chondrodysplasia

Published:2019-12-04 Issue:3 Volume:35 Page:540-549
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Noda Hiroshi¹,Guo Jun¹,Khatri Ashok¹,Dean Thomas¹,Reyes Monica¹,Armanini Michael¹²³,Brooks Daniel J¹²³,Martins Janaina S¹,Schipani Ernestina⁴,Bouxsein Mary L¹²³,Demay Marie B¹,Potts John T¹,Jüppner Harald¹,Gardella Thomas J¹^ORCID

Affiliation:

1. Endocrine Unit, Massachusetts General Hospital, and Harvard Medical School Boston MA USA

2. Department of Orthopedic Surgery, Harvard Medical School Boston MA USA

3. Center for Advanced Orthopedic StudiesBeth Israel Deaconess Medical Center Boston MA USA

4. University of Michigan Ann Arbor MI USA

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbmr.3913

Reference53 articles.

1. [About atypical chondrodystrophy (achondroplasia) and an as yet unspecified congenital growth disorder of the bony system: metaphyseal dysostosis] Über atypische chondrodystrophie (achondroplasie) und über eine noch nicht beschriebene angeborene wachstumsstörung des knochensystems: metaphysäre dysostosis;Jansen M.;Zeitschrift Orthopädie Chirurgie,1934

2. A Constitutively Active Mutant PTH-PTHrP Receptor in Jansen-Type Metaphyseal Chondrodysplasia

3. Calcium metabolism in the jansen type of metaphyseal dysplasia

4. Hypercalcemia due to constitutive activity of the parathyroid hormone (PTH)/PTH-related peptide receptor: comparison with primary hyperparathyroidism

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ocular findings in Jansen metaphyseal chondrodysplasia;JBMR Plus;2024-07-12

2. G protein-coupled receptor (GPCR) gene variants and human genetic disease;Critical Reviews in Clinical Laboratory Sciences;2024-03-18

3. Backbone Modification Provides a Long-Acting Inverse Agonist of Pathogenic, Constitutively Active PTH1R Variants;Journal of the American Chemical Society;2024-02-28

4. Substantially Delayed Maturation of Growth Plate Chondrocytes in “Humanized” PTH1R Mice with the H223R Mutation of Jansen's Disease;JBMR Plus;2023-08-15

5. Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken Syndrome;Communications Biology;2023-06-02