Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cellsviaTopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements-Reference-Cited by-同舟云学术

Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cellsviaTopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements

Published:2016-11-22 Issue:4 Volume:140 Page:864-876
ISSN:0020-7136
Container-title:International Journal of Cancer
language:en
Short-container-title:Int. J. Cancer

Author:

Biechonski Shahar¹,Gourevich Dana¹²,Rall Melanie³,Aqaqe Nasma¹,Yassin Muhammad¹,Zipin-Roitman Adi¹,Trakhtenbrot Luba⁴,Olender Leonid¹,Raz Yael¹⁵,Jaffa Ariel J.⁶⁷,Grisaru Dan⁵⁷,Wiesmuller Lisa³,Elad David²,Milyavsky Michael¹^ORCID

Affiliation:

1. Department of Pathology, Sackler Faculty of Medicine; Tel-Aviv University; Tel-Aviv Israel

2. Department of Biomedical Engineering, Faculty of Engineering; Tel Aviv University; Tel Aviv Israel

3. Department of Obstetrics and Gynecology; Gynecological Oncology, University of Ulm; Ulm Germany

4. Cancer Research Centre, Sheba Medical Centre, Tel Hashomer; Israel

5. Department of Obstetrics and Gynecology; Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center; Tel-Aviv Israel

6. Ultrasound Unit in Obstetrics and Gynecology; Lis Maternity Hospital, Tel Aviv Sourasky Medical Center; Tel-Aviv Israel

7. Sackler Faculty of Medicine; Tel-Aviv University; Tel-Aviv Israel

Funder

European Union

The Israel Cancer Association, Dotan Research Center in Hemato-Oncology, Dan David post-doctoral scholarship, German Research Foundation

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference50 articles.

1. Dietary flavonoids: bioavailability, metabolic effects, and safety;Ross;Annu Rev Nutr,2002

2. Distinct mechanisms of DNA damage in apoptosis induced by quercetin and luteolin;Yamashita;Free Radic Res,2000

3. Bioflavonoids as poisons of human topoisomerase II alpha and II beta;Bandele;Biochemistry,2007

4. The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs;Matter;Biochem Biophys Res Commun,1992

5. Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells;Chen;Biochem Pharmacol,2005

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