Calibration-free inverse modeling of ion-exchange chromatography in industrial antibody purification-Reference-Cited by-同舟云学术

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Calibration-free inverse modeling of ion-exchange chromatography in industrial antibody purification

Published:2015-06-13 Issue:2 Volume:16 Page:107-113
ISSN:1618-0240
Container-title:Engineering in Life Sciences
language:en
Short-container-title:Eng. Life Sci.

Author:

Hahn Tobias¹,Huuk Thiemo¹,Osberghaus Anna¹,Doninger Katharina²,Nath Susanne²,Hepbildikler Stefan²,Heuveline Vincent³,Hubbuch Jürgen¹

Affiliation:

1. Biomolecular Separation Engineering; Karlsruhe Institute of Technology (KIT); Karlsruhe Germany

2. Pharmaceutical Biotech Production; Roche Diagnostics GmbH; Penzberg Germany

3. Engineering Mathematics and Computing Lab; Heidelberg University; Heidelberg Germany

Funder

EURO TRANS-BIO

Publisher

Wiley

Subject

Bioengineering,Environmental Engineering,Biotechnology

Reference19 articles.

1. Twenty Thousand Years of Biotech - From “Traditional” to “Modern Biotechnology”

2. Downstream processing of monoclonal antibodies-application of platform approaches;Shukla;J. Chromatogr. B,2007

3. Recovery and purification process development for monoclonal antibody production;Liu;mAbs,2010

4. Design strategies for integrated protein purification processes: challenges, progress and outlook;Nfor;J. Chem. Technol. Biotechnol.,2008

5. Optimal integration of directly combined hydrophobic interaction and ion exchange chromatography purification processes;Helling;Chem. Eng. Technol.,2012

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mechanistic Modeling of Multimodal Chromatography for Separation of a Monoclonal Antibody from Product-Related Impurities: Fab Fragment and Aggregates;2024

2. Industrial ion-exchange chromatography development using discontinuous Galerkin methods coupled with forward sensitivity analysis;Journal of Chromatography A;2023-01

3. A multiscale modeling method for therapeutic antibodies in ion exchange chromatography;Biotechnology and Bioengineering;2022-10-24

4. The use of predictive models to develop chromatography-based purification processes;Frontiers in Bioengineering and Biotechnology;2022-10-12

5. Exploration of fiber-based cation exchange adsorbents for the removal of monoclonal antibody aggregates;Journal of Chromatography A;2021-09

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