Fruit and vegetable intake and the risk of arterial hypertension in China: A prospective cohort study

Author:

He Zhi1,Jia Yanhui1,Li Jianxin1,Cao Jie1,Liu Fangchao1,Li Hongfan1,Chen Jichun1,Hu Dongsheng23,Shen Chong4,Zhao Yingxin5,Liu Xiaoqing6,Yu Ling7,Huang Jianfeng1,Lu Xiangfeng1ORCID,Gu Dongfeng1,Chen Shufeng1ORCID

Affiliation:

1. Key Laboratory of Cardiovascular Epidemiology, Department of Epidemiology, Fuwai Hospital Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases Beijing China

2. Department of Epidemiology and Health Statistics, College of Public Health Zhengzhou University Zhengzhou Henan China

3. Department of Biostatistics and Epidemiology, School of Public Health Shenzhen University Shenzhen Guangdong China

4. Department of Epidemiology and Biostatistics, Center for Global Health, School of Public Health Nanjing Medical University Nanjing Jiangsu China

5. Cardio‐Cerebrovascular Control and Research Center, Institute of Basic Medicine Shandong First Medical University (Shandong Academy of Medicine Sciences) Jinan Shandong China

6. Division of Epidemiology Guangdong Provincial People's Hospital and Cardiovascular Institute Guangzhou Guangdong China

7. Department of Cardiology Fujian Provincial Hospital Fuzhou Fujian China

Abstract

AbstractBackgroundPopulation‐based epidemiological evidence regarding the association between fruit and vegetable intake and the incidence of hypertension is inconsistent. This prospective cohort study aimed to investigate the association between fruit and vegetable intake and the risk of new‐onset hypertension.MethodsBased on the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China (China‐PAR), 58,981 Chinese adults without hypertension at baseline were included. Information on fruit and vegetable intake was collected using a food‐frequency questionnaire. Cox proportional hazards models were performed to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) of incident hypertension.ResultsDuring 640,795 person‐years of follow‐up, 21,008 new cases of hypertension were recorded. Compared with participants in the lowest quintile (Q1) of total fruit and vegetable (TFV) intake, the HRs (95% CIs) of incident hypertension were 0.90 (0.86–0.95), 0.85 (0.81–0.90), 0.82 (0.78–0.86), and 0.83 (0.78–0.88) for the Q2 to Q5 group (ptrend < 0.001), respectively. In further analyses categorizing participants according to the recommended intake level (500 g/day), we found that increasing the intake of TFV, even though it was still insufficient for the recommendation, also had a protective effect against the incident hypertension. When considering the intake of fruit or vegetable separately, we found similar trends as the TFV intake.ConclusionThese results suggest that a higher intake of fruit and vegetable is beneficial for preventing hypertension in Chinese adults.

Funder

National Natural Science Foundation of China

Publisher

Wiley

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