Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2 : A genome‐wide association study in over 12,000 non‐demented participants-Reference-Cited by-同舟云学术

Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2 : A genome‐wide association study in over 12,000 non‐demented participants

Published:2021-05-18 Issue:10 Volume:17 Page:1663-1674
ISSN:1552-5260
Container-title:Alzheimer's & Dementia
language:en
Short-container-title:Alzheimer's & Dementia

Author:

Damotte Vincent¹,Lee Sven J.²³,Chouraki Vincent¹⁴,Grenier‐Boley Benjamin¹,Simino Jeannette⁵,Adams Hieab⁶,Tosto Giuseppe⁷⁸,White Charles⁹¹⁰,Terzikhan Natalie³¹¹,Cruchaga Carlos¹²,Knol Maria J.³,Li Shuo¹³¹⁴,Schraen Susanna¹⁵,Grove Megan L.¹⁶,Satizabal Claudia⁴¹⁴,Amin Najaf³,Berr Claudine¹⁷,Younkin Steven¹⁸,Gottesman Rebecca F.¹⁹²⁰,Buée Luc¹²¹,Beiser Alexa⁴¹³¹⁴,Knopman David S.²²,Uitterlinden Andre²³,DeCarli Charles²⁴,Bressler Jan¹⁶,DeStefano Anita⁴¹³¹⁴,Dartigues Jean‐François²⁵,Yang Qiong¹³¹⁴,Boerwinkle Eric¹⁶²⁶,Tzourio Christophe²⁵,Fornage Myriam¹⁶²⁷,Ikram M. Arfan⁶,Amouyel Philippe¹,Jager Phil⁹¹⁰²⁸,Reitz Christiane⁷⁸²⁹³⁰,Mosley Thomas H.³¹,Lambert Jean‐Charles¹,Seshadri Sudha⁴¹⁴³²,Duijn Cornelia M.³³³,

Affiliation:

1. Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille Lille France

2. Alzheimer Center Amsterdam, Department of Neurology Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC Amsterdam the Netherlands

3. Department of Epidemiology Erasmus Medical Center Rotterdam the Netherlands

4. Department of Neurology Boston University School of Medicine Boston Massachusetts USA

5. Gertrude C. Ford MIND Center Department of Data Science John D. Bower School of Population Health University of Mississippi Medical Center Jackson Mississippi USA

6. Departments of Epidemiology Neurology and Radiology and Nuclear Medicine Erasmus Medical Center Rotterdam the Netherlands

7. Taub Institute for Research on Alzheimer's Disease and the Aging Brain Columbia University New York New York USA

8. Gertrude H. Sergievsky Center Columbia University New York New York USA

9. Program in Translational NeuroPsychiatric Genomics Institute for the Neurosciences Departments of Neurology and Psychiatry Brigham and Women's Hospital Boston Massachusetts USA

10. Program in Medical and Population Genetics Broad Institute Cambridge Massachusetts USA

11. Department of Respiratory Medicine Ghent University Hospital Ghent Belgium

12. Department of Psychiatry Washington University in St. Louis Saint Louis Missouri USA

13. Department of Biostatistics Boston University School of Public Health Boston Massachusetts USA

14. The Framingham Heart Study Framingham Massachusetts USA

15. Université Lille, CHU‐Lille, Inserm UF de Neurobiologie, CBPG Lille France

16. Human Genetics Center, Department of Epidemiology Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston Houston Texas USA

17. INSERM U1061 University of Montpellier Montpellier France

18. Department of Neuroscience Mayo Clinic, Jacksonville Florida USA

19. Department of Neurology Johns Hopkins University School of Medicine Baltimore Maryland USA

20. Department of Epidemiology Johns Hopkins Bloomberg School of Public Health Baltimore Maryland USA

21. Institut National de la Santé et de la Recherche Medicale (INSERM Université de Lille Lille France

22. Department of Neurology Mayo Clinic College of Medicine Rochester Minnesota USA

23. Department of Internal Medicine Erasmus Medical Center Rotterdam the Netherlands

24. Department of Neurology University of California at Davis Davis California USA

25. Bordeaux Population Health Research Center INSERM, UMR1219 Bordeaux University Bordeaux France

26. Human Genome Sequencing Center Baylor College of Medicine Houston Texas USA

27. Brown Foundation Institute of Molecular Medicine McGovern Medical School The University of Texas Health Science Center at Houston Houston Texas USA

28. Center for Translational & Systems Neuroimmunology Department of Neurology Columbia University Medical Center, New York New York New York USA

29. Department of Neurology Columbia University New York New York USA

30. Department of Epidemiology Columbia University New York New York USA

31. Department of Medicine Gertrude C. Ford MIND Center University of Mississippi Medical Center Jackson Mississippi USA

32. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases UT Health San Antonio San Antonio Texas USA

33. Nuffield Department of Population Health University of Oxford Oxford UK

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Clinical Neurology,Developmental Neuroscience,Health Policy,Epidemiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/alz.12333

Reference50 articles.

1. Trafficking and Proteolytic Processing of APP

2. National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

3. Cerebral amyloid angiopathy in the elderly

4. Platelets Are the Primary Source of Amyloid β-Peptide in Human Blood

5. Amyloid precursor protein in pancreatic islets

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