Plasma P‐tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular disease

Author:

Chong Joyce R.12,Ashton Nicholas J.3456,Karikari Thomas K.3,Tanaka Tomotaka278,Saridin Francis N.12,Reilhac Anthonin8,Robins Edward G.89,Nai Ying‐Hwey8,Vrooman Henri10,Hilal Saima1211,Zetterberg Henrik3121314,Blennow Kaj312,Lai Mitchell K.P.12ORCID,Chen Christopher P.12

Affiliation:

1. Department of Pharmacology Yong Loo Lin School of Medicine National University of Singapore Kent Ridge Singapore

2. Memory Aging and Cognition Centre National University Health Systems Kent Ridge Singapore

3. Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy at the University of Gothenburg Mölndal Sweden

4. Wallenberg Centre for Molecular and Translational Medicine University of Gothenburg Gothenburg Sweden

5. Psychology and Neuroscience King's College London Institute of Psychiatry Maurice Wohl Institute Clinical Neuroscience Institute London UK

6. NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia at South London and Maudsley NHS Foundation London UK

7. Department of Neurology National Cerebral and Cardiovascular Center Suita Osaka Japan

8. Clinical Imaging Research Centre Yong Loo Lin School of Medicine National University of Singapore Kent Ridge Singapore

9. Technology and Research, Biopolis Singapore Bioimaging Consortium A*Star Agency for Science Singapore

10. Department of Radiology and Nuclear Medicine Erasmus Medical Center Rotterdam the Netherlands

11. Saw Swee Hock School of Public Health National University of Singapore and National University Health System Kent Ridge Singapore

12. Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden

13. UK Dementia Research Institute at UCL London UK

14. Department of Neurodegenerative Disease UCL Institute of Neurology London UK

Funder

National Medical Research Council

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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