Expiratory Velopharyngeal Obstruction: Sleep Endoscopy‐Guided Treatment Strategies to Prevent Oral Breathing During Sleep

Author:

Hsu Ying‐Shuo1234ORCID,Ke Yuan‐Kai5,Kuo Terry B. J.12678,Chang Yi9,Jacobowitz Ofer10ORCID,Lin Chia‐Mo111213,Lo Shih‐Chieh114,Yang Cheryl C. H.1267

Affiliation:

1. Institute of Brain Science National Yang Ming Chiao Tung University Taipei Taiwan (ROC)

2. Sleep Research Center National Yang Ming Chiao Tung University Taipei Taiwan (ROC)

3. Department of Otolaryngology Shin Kong Wu‐Ho‐Su Memorial Hospital Taipei Taiwan (ROC)

4. School of Medicine Fu Jen Catholic University New Taipei City Taiwan (ROC)

5. Department of Oral & Maxillofacial Surgery, Taipei Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation New Taipei City Taiwan (ROC)

6. Brain Research Center National Yang Ming Chiao Tung University Taipei Taiwan (ROC)

7. Department of Education and Research Taipei City Hospital Taipei Taiwan (ROC)

8. Clinical Research Center Taoyuan Psychiatric Center Ministry of Health and Welfare Taoyuan Taiwan (ROC)

9. Department of Anesthesiology Shin Kong Wu Ho‐Su Memorial Hospital Taipei Taiwan (ROC)

10. Sleep department ENT and Allergy Associates New York New York USA

11. Division of Chest Medicine Shin Kong Wu Ho‐Su Memorial Hospital Taipei City Taiwan (ROC)

12. Department of Chemistry Fu Jen Catholic University New Taipei City Taiwan (ROC)

13. Graduate Institute of Biomedical and Pharmaceutical Science Fu Jen Catholic University New Taipei City Taiwan (ROC)

14. Leading Dental Group Taipei Taiwan (ROC)

Abstract

AbstractObjectiveObstructive sleep apnea (OSA) is a prevalent disorder, with oral breathing influencing its severity. Expiratory velopharyngeal obstruction (EVO), observed during drug‐induced sleep endoscopy (DISE), may contribute to oral breathing in OSA patients. EVO results in obstruction between the pharynx and nasal cavity during expiration. This study aims to identify factors associated with positive EVO during DISE.Study DesignCase series.SettingTertiary Medical Center.MethodsSeventy‐two OSA patients underwent clinical evaluation, polysomnography, and DISE, utilizing interventions like intraoral negative airway pressure (iNAP), mouth closure, and oral appliances (OAs) in supine positions with head rotation. The findings, classified under velopharynx, oropharynx, tongue base, epiglottis, included the presence of EVO.ResultsThe results demonstrated that interventions including mouth closure and iNAP were associated with increased observation of EVO (43.1% and 34.7%) compared to OA (20.1%). However, head rotation was associated with decreased presence of EVO during DISE compare to supine (26% vs 35.8%). Noticeably, per 1 year increase of age was associated with an increased odds of EVO (odds ratio: 1.03, 95% confidence interval: 1.01‐1.06). However, no other baseline characteristics were significantly associated the odds of EVO.ConclusionOur study reveals the effectiveness of head rotation and OA in reducing EVO and improving mouth breathing in OSA patients, offering valuable insights for future treatment strategies.

Publisher

Wiley

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