Population pharmacokinetic‐pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease
Author:
Affiliation:
1. Eisai Co., Ltd. Tokyo Japan
2. Eisai Inc. Nutley New Jersey USA
3. Eisai Ltd. Hatfield UK
Publisher
Wiley
Subject
Pharmacology (medical),Modeling and Simulation
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12862
Reference42 articles.
1. Alzheimer's Association.Alzheimer's disease facts and figures;2021. Available from:https://www.alz.org/media/Documents/alzheimers‐facts‐and‐figures.pdf
2. Predictive value of APOE- 4 allele for progression from MCI to AD-type dementia: a meta-analysis
3. Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease
4. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
5. Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease
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