Revisiting gap locations in amino acid sequence alignments and a proposal for a method to improve them by introducing solvent accessibility

Author:

Hijikata Atsushi1,Yura Kei23,Noguti Tosiyuki14,Go Mitiko567

Affiliation:

1. Division of Biological Science, Graduate School of Science, Nagoya University, Furo, Chikusa, Nagoya 464‐8602, Japan

2. Computational Biology, Graduate School of Humanities and Sciences, Ochanomizu University, 2‐1‐1 Otsuka, Bunkyo, Tokyo 112‐8610, Japan

3. Center for Informational Biology, Ochanomizu University, 2‐1‐1 Otsuka, Bunkyo, Tokyo 112‐8610, Japan

4. Oasis Daini Hospital, 2‐3‐30 Higasi‐Tsurusaki, Ooita 870‐0103, Japan

5. Department of Bioscience, Faculty of Bioscience, Nagahama Institute of Bio‐Science and Technology, 1266 Tamura, Nagahama, Shiga 526‐0829, Japan

6. Tokyo Medical and Dental University, 1‐5‐45 Yushima, Bunkyo, Tokyo 113‐8510, Japan

7. Research Organization of Information and Systems, 4‐3‐13, Toranomon, Minato, Tokyo 105‐0001, Japan

Funder

Targeted Proteins Research Program (TPRP) from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan

Grant-in-Aid for Scientific Research (B) from the Japan Society for the Promotion of Science KAKENHI

Unknown funding agency

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

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