Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor-Reference-Cited by-同舟云学术

Nonclinical pharmacokinetics and metabolism of EPZ-5676, a novel DOT1L histone methyltransferase inhibitor

Published:2014-02-14 Issue:4 Volume:35 Page:237-252
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm. Drug Dispos.

Author:

Basavapathruni Aravind¹,Olhava Edward J.¹,Daigle Scott R.¹,Therkelsen Carly A.¹,Jin Lei¹,Boriack-Sjodin P. Ann¹,Allain Christina J.¹,Klaus Christine R.¹,Raimondi Alejandra¹,Scott Margaret Porter¹,Dovletoglou Angelos¹,Richon Victoria M.¹,Pollock Roy M.¹,Copeland Robert A.¹,Moyer Mikel P.¹,Chesworth Richard¹,Pearson Paul G.¹,Waters Nigel J.¹

Affiliation:

1. Epizyme Inc.; 400 Technology Square Cambridge MA USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Reference24 articles.

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5. ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation;Nakamura;Mol Cell,2002

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