Path (Probe ADME and Test Hypotheses): A Useful Approach Enabling Hypothesis-Driven ADME Optimization

Author:

Bell Leslie,Skolnik Suzanne,Bednarczyk Dallas

Publisher

John Wiley & Sons, Inc.

Reference60 articles.

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3. Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes;Obach;Drug Metabolism and Disposition,1999

4. High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes;Wohnsland;Journal of Medicinal Chemistry,2001

5. Towards prediction of in vivo intestinal absorption using a 96-well Caco-2 assay;Skolnik;Journal of Pharmaceutical Sciences,2010

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