Synthesis and Biological Evaluation of Sigma‐1 (σ1) Receptor Ligands Based on Phenyl‐1,2,4‐oxadiazole Derivatives

Author:

Cao Xudong1,Yao Zhongyuan2,Dou Fei2,Zhang Yifang1,Qiu Yinli2,Zhao Song2,Xu Xiangqing2,Liu Xin1,Liu Bi‐Feng1,Chen Yin23,Zhang Guisen12

Affiliation:

1. Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and TechnologyHuazhong University of Science and Technology Wuhan 430074 P. R. China

2. Jiangsu Nhwa Pharmaceutical Co., Ltd. 69 Democratic South Road Xuzhou 221116 P. R. China

3. Jiangsu Marine Resources Development Research Institute, Lianyungang 222005 P. R. China

Funder

China Postdoctoral Science Foundation

NSFC

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Reference40 articles.

1. G. P. Martin C. Marriott I. W. Kellaway ‘The effect of natural surfactants on the pheological properties of mucus [proceedings]’ J. Pharm. Pharmacol.1976 28 Suppl: 76P.

2. M. Hanner F. F. Moebius A. Flandorfer H. G. Knaus J. Striessnig E. Kempner H. Glossmann ‘Purification molecular cloning and expression of the mammalian σ1-binding site’ Proc. Natl. Acad. Sci. USA1996 93 8072–8077.

3. T. P. Su ‘Evidence for sigma opioid receptor: binding of [3H]-SKF-10047 to etorphine-inaccessible sites in guinea-pig brain’ J. Pharmacol. Exp. Ther.1982 223 284–290.

4. T.-P. Su T. Hayashi T. Maurice S. Buch A. E. Ruoho ‘The σ1receptor chaperone as an inter-organelle signaling modulator’ Trends Pharmacol. Sci.2010 31 557–566.

5. S.-Y. Tsai T. Hayashi T. Mori T.-P. Su ‘σ1Receptor chaperones and diseases’ Cent. Nerv. Syst. Agents Med. Chem.2009 9 184–189.

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