1. Marine Biopharmaceutical Institute; Second Military Medical University; Xiangyin Road 800 Shanghai 200433 P. R. China
2. Marine Science and Technology College; Zhejiang Ocean University; 1 South Haida Road Zhoushan 316022 P. R. China
3. Department of Biochemistry and Molecular Biology; College of Basic Medical Sciences; Second Military Medical University; Shanghai 200433 P. R. China
4. School of Food and Pharmacy; Zhejiang Ocean University; 1 South Haida Road Zhoushan 316022 P. R. China