Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor-Reference-Cited by-同舟云学术

Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor

Published:2018-03 Issue:3 Volume:15 Page:e1700518
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chem. Biodiversity

Author:

Ameri Alieh¹,Khodarahmi Ghadamali²,Forootanfar Hamid³,Hassanzadeh Farshid²,Hakimelahi Gholam-Hosein²⁴

Affiliation:

1. Department of Medicinal Chemistry; Faculty of Pharmacy; Kerman University of Medical Sciences; Kerman Iran

2. Department of Medicinal Chemistry; Faculty of Pharmacy; Isfahan University of Medical Sciences; Isfahan Iran

3. Department of Pharmaceutical Biotechnology; Faculty of Pharmacy; Kerman University of Medical Sciences; Kerman Iran

4. Institute of Chemistry; Academia Sinica; Nankang Taipei Taiwan

Funder

Isfahan University of Medical Sciences

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Reference45 articles.

1. Design, Synthesis, Cytotoxic Evaluation and Tubulin Inhibitory Activity of 4-Aryl-5-(3,4,5-trimethoxyphenyl)-2-alkylthio-1H-imidazole Derivatives;Assadieskandar;Bioorg. Med. Chem.,2013

2. Synthesis, Biochemical and Molecular Modelling Studies of Antiproliferative Azetidinones Causing Microtubule Disruption and Mitotic Catastrophe;O'Boyle;Eur. J. Med. Chem.,2011

3. Design, Synthesis, In vitro, and In vivo Anticancer and Antiangiogenic Activity of Novel 3-Arylaminobenzofuran Derivatives Targeting the Colchicine Site on Tubulin;Romagnoli;J. Med. Chem.,2015

4. Synthesis and Biological Evaluation of 2-Substituted-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl Thiazoles as Anticancer Agents;Romagnoli;Bioorg. Med. Chem.,2012

5. Synthesis and Cytotoxicity of 3,4-Disubstituted-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazoles and Novel 5,6-Dihydro-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole Derivatives Bearing 3,4,5-Trimethoxyphenyl Moiety;Zhao;Bioorg. Med. Chem. Lett.,2012

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