Pristimerin Induces Autophagy‐Mediated Cell Death in K562 Cells through the ROS/JNK Signaling Pathway

Author:

Liu Yingxiang12,Ren Ziting12,Li Xiang1,Zhong Jing13,Bi Yun1,Li Rui12,Zhao Qun1,Yu Xianjun14ORCID

Affiliation:

1. Laboratory of Inflammation and Molecular Pharmacology, School of Basic Medical Sciences & Biomedical Research Institute Hubei University of Medicine Shiyan 442000 P. R. China

2. First Clinical College Hubei University of Medicine Shiyan 442000 P. R. China

3. Hubei Key Laboratory of Natural Products Research and Development China Three Gorges University Yichang 443002 P. R. China

4. Institute of Medicine and Nursing Hubei University of Medicine Shiyan 442000 P. R. China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

Reference34 articles.

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2. B. J. Druker F. Guilhot S. G. O′Brien I. Gathmann H. Kantarjian N. Gattermann M. W. Deininger R. T. Silver J. M. Goldman R. M. Stone F. Cervantes A. Hochhaus B. L. Powell J. L. Gabrilove P. Rousselot J. Reiffers J. J. Cornelissen T. Hughes H. Agis T. Fischer G. Verhoef J. Shepherd G. Saglio A. Gratwohl J. L. Nielsen J. P. Radich B. Simonsson K. Taylor M. Baccarani C. So L. Letvak R. A. Larson ‘Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia’ N. Engl. J. Med.2006 355 2408–2417.

3. D.-Q. Luo H. Wang X. Tian H.-J. Shao J.-K. Liu ‘Antifungal properties of pristimerin and celastrol isolated fromCelastrus hypoleucus’ Pest Manage. Sci.2005 61 85–90.

4. F. P. Gullo J. C. Sardi V. A. Santos F. Sangalli-Leite N. S. Pitangui S. A. Rossi E. S. A. C. de Paula L. A. Soares J. F. Silva H. C. Oliveira M. Furlan D. H. Silva V. S. Bolzani M. J. Mendes-Giannini A. M. Fusco-Almeida ‘Antifungal activity of maytenin and pristimerin’ Evid. Based Complement. Alternat. Med.2012 2012 340787.

5. A. H. Jeller D. H. S. Silva L. M. Liao V. da S. Bolzani M. Furlan ‘Antioxidant phenolic and quinonemethide triterpenes fromCheiloclinium cognatum’ Phytochemistry2004 65 1977–1982.

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