Restoring Histone Deacetylase Activity by Waste Product Release. A View from Molecular Mechanics Simulations with Mammalian HDAC8
Author:
Publisher
Wiley
Subject
Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbdv.201400314/fullpdf
Reference28 articles.
1. HDAC8 substrates: Histones and beyond
2. Histone Deacetylase Inhibitors: Overview and Perspectives
3. The many roles of histone deacetylases in development and physiology: implications for disease and therapy
4. Catalytic Activity and Inhibition of Human Histone Deacetylase 8 Is Dependent on the Identity of the Active Site Metal Ion
5. Structural Studies of Human Histone Deacetylase 8 and Its Site-Specific Variants Complexed with Substrate and Inhibitors,
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