Glycine N ‐Methylation in NGR‐Tagged Nanocarriers Prevents Isoaspartate Formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing-Reference-Cited by-同舟云学术

Glycine N ‐Methylation in NGR‐Tagged Nanocarriers Prevents Isoaspartate Formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing

Published:2017-07-31 Issue:36 Volume:27 Page:1701245
ISSN:1616-301X
Container-title:Advanced Functional Materials
language:en
Short-container-title:Adv. Funct. Mater.

Author:

Corti Angelo¹,Gasparri Anna Maria²,Ghitti Michela²,Sacchi Angelina²,Sudati Francesco²,Fiocchi Martina²,Buttiglione Valentina²,Perani Laura²,Gori Alessandro³,Valtorta Silvia²⁴,Moresco Rosa Maria²⁴,Pastorino Fabio⁵,Ponzoni Mirco⁵,Musco Giovanna²,Curnis Flavio²^ORCID

Affiliation:

1. IRCCS San Raffaele Scientific Institute and Vita Salute San Raffaele University Milan 20132 Italy

2. IRCCS San Raffaele Scientific Institute Via Olgettina, 58 20132 Milan Italy

3. Istituto di Chimica del Riconoscimento MolecolareC.N.R. Via Mario Bianco 9 20131 Milan Italy

4. Department of Medicine and SurgeryUniversity of Milano‐Bicocca via Cadore 48 20900 Monza Italy

5. Istituto G. Gaslini Via G. Gaslini 5 16148 Genoa Italy

Funder

Association for International Cancer Research

Ministero della Salute

Associazione Italiana per la Ricerca sul Cancro

Publisher

Wiley

Subject

Electrochemistry,Condensed Matter Physics,Biomaterials,Electronic, Optical and Magnetic Materials

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/adfm.201701245

Reference36 articles.

1. Tumor Vasculature Targeting Through NGR Peptide-Based Drug Delivery Systems

2. Enhancement of tumor necrosis factor α antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)

3. Targeted Delivery of IFNγ to Tumor Vessels Uncouples Antitumor from Counterregulatory Mechanisms

4. High-yield expression, purification and characterization of tumor-targeted IFN-α2a

5. Infarction of tumor vessels by NGR-peptide–directed targeting of tissue factor: experimental results and first-in-man experience

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