1. Faculty of Pharmaceutical Sciences; Hokkaido University; Kita-12 Kita-12Nishi-6 Kita-ku Sapporo 060-0812 Japan
2. Department of Pediatric Dentistry; School of Dentistry; Health Sciences University of Hokkaido; Kita-121757 Kanazawa Ishikari-Tobetsu Hokkaido 061-0293 Japan
3. Department of Pharmacology; School of Dentistry; Health Sciences University of Hokkaido; Kita-121757 Kanazawa Kita-12Ishikari-Tobetsu Hokkaido 061-0293 Japan