A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease-Reference-Cited by-同舟云学术

A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease

Published:2017-01-31 Issue:4 Volume:18 Page:402-412
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Marques André R. A.¹²,Willems Lianne I.³⁴,Herrera Moro Daniela¹,Florea Bogdan I.³,Scheij Saskia¹,Ottenhoff Roelof¹,van Roomen Cindy P. A. A.¹,Verhoek Marri⁵,Nelson Jessica K.¹,Kallemeijn Wouter W.⁵,Biela-Banas Anna⁶,Martin Olivier R.⁶,Cachón-González M. Begoña⁷,Kim Nee Na⁷,Cox Timothy M.⁷,Boot Rolf G.⁵,Overkleeft Herman S.³,Aerts Johannes M. F. G.¹⁵

Affiliation:

1. Department of Biochemistry; Academic Medical Center; University of Amsterdam; Meibergdreef 15 1105 AZ Amsterdam The Netherlands

2. Present address: Institute of Biochemistry; Christian-Albrechts-University of Kiel; Otto-Hahn-Platz 9 24098 Kiel Germany

3. Department of Bio-organic Synthesis; Leiden Institute of Chemistry; Leiden University; Einsteeinweg 55 2300 RA Leiden The Netherlands

4. Present address: Department of Chemistry; Simon Fraser University; 8888 University Drive Burnaby V5A 1S6 BC Canada

5. Department of Biochemistry; Leiden Institute of Chemistry; Leiden University; Einsteinweg 55 2300 RA Leiden The Netherlands

6. Institute of Organic and Analytical Chemistry; Université D'Orléans; Rue de Chartres B. P. 6759 45100 Orléans France

7. Department of Medicine; University of Cambridge; Addenbrooke's Hospital; Hills Road Cambridge CB2 2QQ UK

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference47 articles.

1. Insights into Krabbe disease from structures of galactocerebrosidase

2. Expression and processing of recombinant human galactosylceramidase

3. Structural snapshots illustrate the catalytic cycle of -galactocerebrosidase, the defective enzyme in Krabbe disease

4. Psychosine-induced apoptosis and cytokine activation in immune peripheral cells of Krabbe patients

5. The twitcher mouse: accumulation of galactosylsphingosine and pathology of the sciatic nerve

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