Hepatocyte-Specific Delivery of siRNAs Conjugated to Novel Non-nucleosidic TrivalentN-Acetylgalactosamine Elicits Robust Gene Silencing in Vivo-Reference-Cited by-同舟云学术

Hepatocyte-Specific Delivery of siRNAs Conjugated to Novel Non-nucleosidic TrivalentN-Acetylgalactosamine Elicits Robust Gene Silencing in Vivo

Published:2015-03-18 Issue:6 Volume:16 Page:903-908
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Rajeev Kallanthottathil G.,Nair Jayaprakash K.,Jayaraman Muthusamy,Charisse Klaus,Taneja Nate,O'Shea Jonathan,Willoughby Jennifer L. S.,Yucius Kristina,Nguyen Tuyen,Shulga-Morskaya Svetlana,Milstein Stuart,Liebow Abigail,Querbes William,Borodovsky Anna,Fitzgerald Kevin,Maier Martin A.,Manoharan Muthiah

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbic.201500023/fullpdf

Reference40 articles.

1. The RNAi revolution

2. RNAi therapeutics: a potential new class of pharmaceutical drugs

3. Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing

4. siRNA: novel therapeutics from functional genomics

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