Parallel Post-Polyketide Synthase Modification Mechanism Involved in FD-891 Biosynthesis inStreptomyces graminofaciensA-8890
Author:
Affiliation:
1. Department of Chemistry; Tokyo Institute of Technology; 2-12-1 O-okayama Meguro-ku Tokyo 152-8551 Japan
2. Department of Chemistry and Materials Science; Tokyo Institute of Technology; 2-12-1 O-okayama Meguro-ku Tokyo 152-8551 Japan
Publisher
Wiley
Subject
Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbic.201500533/fullpdf
Reference31 articles.
1. Isolation and characterization of new 18-membered macrolides FD-891 and FD-892.
2. Structure Revision of FD-891, a 16-Membered Macrolide Antibiotic
3. The cytotoxic macrolide FD-891 induces caspase-8-dependent mitochondrial release of cytochrome c and subsequent apoptosis in human leukemia Jurkat cells
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