A Versatile and Convenient Synthesis of 34 S-Labeled Phosphorothioate Oligonucleotides-Reference-Cited by-同舟云学术

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A Versatile and Convenient Synthesis of 34 S-Labeled Phosphorothioate Oligonucleotides

Published:2018-09-13 Issue:19 Volume:19 Page:2114-2119
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Stulz Rouven¹²,Meuller Johan³,Baždarević Dženita¹,Wennberg Huldt Charlotte¹,Strömberg Roger²,Andersson Shalini¹,Dahlén Anders¹^ORCID

Affiliation:

1. Cardiovascular, Renal and Metabolism IMED Biotech Unit; AstraZeneca; Pepparedsleden 1 43150 Mölndal Sweden

2. Department of Biosciences and Nutrition; Karolinska Institutet; NEO Hälsovägen 9 14157 Huddinge Sweden

3. Discovery Sciences IMED Biotech Unit; AstraZeneca; Pepparedsleden 1 43150 Mölndal Sweden

Funder

H2020 European Institute of Innovation and Technology

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbic.201800417/fullpdf

Reference36 articles.

1. RNA-Targeted Therapeutics

2. Development of Therapeutic Splice-Switching Oligonucleotides

3. Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides

4. Oligodeoxynucleotide stability in subcellular extracts and culture media

5. Phosphorothioates, Essential Components of Therapeutic Oligonucleotides

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1. Incorporation of Intracellular NanoSIMS Tracers to Oligonucleotide Conjugates via Strain Promoted Sydnone–Alkyne Cycloaddition;Bioconjugate Chemistry;2024-06-11

2. Intracellular Absolute Quantification of Oligonucleotide Therapeutics by NanoSIMS;Analytical Chemistry;2022-07-13

3. NanoSIMS Imaging Reveals the Impact of Ligand-ASO Conjugate Stability on ASO Subcellular Distribution;Pharmaceutics;2022-02-21

4. 34S-SIL of PCSK9-Active Oligonucleotide as Tools for Accurate Quantification by Mass Spectrometry;Nucleic Acid Therapeutics;2021-10-01

5. Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugates;Drug Discovery Today;2021-10

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