Structural Diversity and Anticancer Activity of Marine-Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive Breast Cancer-Reference-Cited by-同舟云学术

Structural Diversity and Anticancer Activity of Marine-Derived Elastase Inhibitors: Key Features and Mechanisms Mediating the Antimetastatic Effects in Invasive Breast Cancer

Published:2018-03-23 Issue:8 Volume:19 Page:815-825
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Al-Awadhi Fatma H.¹²³,Paul Valerie J.⁴^ORCID,Luesch Hendrik¹²^ORCID

Affiliation:

1. Department of Medicinal Chemistry; University of Florida; 1345 Center Drive Gainesville FL 32610 USA

2. Center for Natural Products; Drug Discovery and Development (CNPD3); University of Florida; 1345 Center Drive Gainesville FL 32610 USA

3. Department of Pharmaceutical Chemistry; Faculty of Pharmacy; Kuwait University; P.O. Box 24923 Safat 13110 Kuwait

4. Smithsonian Marine Station; 701 Seaway Drive Fort Pierce FL 34949 USA

Funder

National Cancer Institute

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference46 articles.

1. Secondary Metabolites from Cyanobacteria: Complex Structures and Powerful Bioactivities

2. Filamentous tropical marine cyanobacteria: a rich source of natural products for anticancer drug discovery

3. Symplocamide A, a Potent Cytotoxin and Chymotrypsin Inhibitor from the Marine Cyanobacterium Symploca sp.

4. Lyngbyastatins 5–7, Potent Elastase Inhibitors from Floridian Marine Cyanobacteria, Lyngbya spp.

5. Lyngbyastatins 8–10, Elastase Inhibitors with Cyclic Depsipeptide Scaffolds Isolated from the Marine Cyanobacterium Lyngbya semiplena

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