Rational Engineering of Hydratase from Lactobacillus acidophilus Reveals Critical Residues Directing Substrate Specificity and Regioselectivity-Reference-Cited by-同舟云学术

Rational Engineering of Hydratase from Lactobacillus acidophilus Reveals Critical Residues Directing Substrate Specificity and Regioselectivity

Published:2019-11-20 Issue:4 Volume:21 Page:550-563
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Eser Bekir Engin¹^ORCID,Poborsky Michal¹,Dai Rongrong¹,Kishino Shigenobu²^ORCID,Ljubic Anita³^ORCID,Takeuchi Michiki²,Jacobsen Charlotte³^ORCID,Ogawa Jun²,Kristensen Peter⁴^ORCID,Guo Zheng¹^ORCID

Affiliation:

1. Department of EngineeringAarhus University Gustav Wieds Vej 10 8000 Aarhus Denmark

2. Division of Applied Life SciencesGraduate School of AgricultureKyoto University Kitashirakawa-oiwakecho Sakyo-ku Kyoto 606-8502 Japan

3. Division of Food Technology, National Food InstituteTechnical University of Denmark Kemitorvet, Building 202 2800 Kgs. Lyngby Denmark

4. Faculty of Engineering and ScienceDepartment of Chemistry and BioscienceAalborg University Frederik Bayers Vej 7H 9220 Aalborg Denmark

Funder

Novo Nordisk Fonden

Aarhus Universitet

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.201900389

Reference64 articles.

2. New lipid science in our inner ecosystem

3. Immunomodulatory activity of a gut microbial metabolite of dietary linoleic acid, 10-hydroxy-cis-12-octadecenoic acid, associated with improved antioxidant/detoxifying defences

5. Production of hydroxy fatty acids by microbial fatty acid-hydroxylation enzymes

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