Creating Flavin Reductase Variants with Thermostable and Solvent‐Tolerant Properties by Rational‐Design Engineering

Author:

Maenpuen Somchart1,Pongsupasa Vinutsada2,Pensook Wiranee1,Anuwan Piyanuch2,Kraivisitkul Napatsorn3,Pinthong Chatchadaporn4,Phonbuppha Jittima2,Luanloet Thikumporn5,Wijma Hein J.6,Fraaije Marco W.6,Lawan Narin7,Chaiyen Pimchai25,Wongnate Thanyaporn2ORCID

Affiliation:

1. Department of BiochemistryFaculty of ScienceBurapha University 169 Long-Hard Bangsaen Road Chonburi 20131 Thailand

2. School of Biomolecular Science and EngineeringVidyasirimedhi Institute of Science and Technology (VISTEC) 555 Moo 1 Payupnai Wangchan Rayong 21210 Thailand

3. Kamnoetvidya Science Academy 999 Moo 1 Payupnai Wangchan Rayong 21210 Thailand

4. Department of ChemistryFaculty of ScienceSrinakharinwirot University 114 Sukhumvit 23 Road Bangkok 10110 Thailand

5. Center for Excellence in Protein and Enzyme TechnologyFaculty of ScienceMahidol University 272 Rama VI Road Ratchathewi Bangkok 10400 Thailand

6. Molecular Enzymology GroupGroningen Biomolecular Sciences and Biotechnology InstituteUniversity of Groningen Nijenborgh 4 9747 AG Groningen The Netherlands

7. Department of ChemistryFaculty of ScienceChiang Mai University 239 Huaykaew Road Suthep Chiang Mai 50200 Thailand

Funder

Thailand Research Fund

Faculty of Science, Chiang Mai University

Vidyasirimedhi Institute of Science and Technology

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

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