Molecular Containers Bind Drugs of Abuse in Vitro and Reverse the Hyperlocomotive Effect of Methamphetamine in Rats

Author:

Ganapati Shweta1,Grabitz Stephanie D.2,Murkli Steven1,Scheffenbichler Flora2,Rudolph Maíra I.2,Zavalij Peter Y.1,Eikermann Matthias2,Isaacs Lyle1ORCID

Affiliation:

1. Department of Chemistry and Biochemistry; University of Maryland; College Park MD 20742 USA

2. Department of Anesthesia; Critical Care and Pain Medicine; Massachusetts General Hospital; Harvard Medical School; Boston MA 02114 USA

Funder

National Cancer Institute

University of Maryland

Merck Inc.

Jeff and Judy Buzen

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Reference49 articles.

1. Facing Addiction in America: The Surgeon General's Report on Alcohol Drugs and Health, 2016 https://www.surgeongeneral.gov/library/2016alcoholdrugshealth/index.html

2. Behavioral Health Trends in the United States https://www.samhsa.gov/data/sites/default/files/NSDUH-FRR1-2014/NSDUH-FRR1-2014.pdf

3. National Drug Threat Assessment 2011 http://www.justice.gov/archive/ndic/pubs44/44849/44849p.pdf

4. Pharmacokinetic strategies for treatment of drug overdose and addiction

5. Biologic Approaches to Treat Substance-Use Disorders

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