Unveiling Two Consecutive Hydroxylations: Mechanisms of Aromatic Hydroxylations Catalyzed by Flavin‐Dependent Monooxygenases for the Biosynthesis of Actinorhodin and Related Antibiotics-Reference-Cited by-同舟云学术

Unveiling Two Consecutive Hydroxylations: Mechanisms of Aromatic Hydroxylations Catalyzed by Flavin‐Dependent Monooxygenases for the Biosynthesis of Actinorhodin and Related Antibiotics

Published:2019-11-27 Issue:5 Volume:21 Page:623-627
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Hashimoto Makoto¹^ORCID,Taguchi Takaaki²^ORCID,Ishikawa Kazuki¹^ORCID,Mori Ryuichiro¹,Hotta Akari¹,Watari Susumu¹,Katakawa Kazuaki¹^ORCID,Kumamoto Takuya³^ORCID,Okamoto Susumu⁴^ORCID,Ichinose Koji¹^ORCID

Affiliation:

1. Research Institute of Pharmaceutical SciencesMusashino University 1-1-20, Shinmachi Nishitokyo-shi Tokyo 202-8585 Japan

2. National Institute of Health Sciences 3-25-26, Tonomachi Kawasaki-ku Kawasaki-shi Kanagawa 210-9501 Japan

3. Graduate School of Biomedical and Health SciencesHiroshima University 1-2-3 Kasumi Minami-ku Hiroshima City Hiroshima 734-8553 Japan

4. National Agriculture and Food Research Organization 2-1-12 Kannondai Tsukuba Ibaraki 305-8642 Japan

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.201900490

Reference26 articles.

1. Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism

2. A Role for Flavin Monooxygenase-Like Enzymes in Auxin Biosynthesis

3. Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum

4. Flavin dependent monooxygenases

5. Two-Component FAD-Dependent Monooxygenases: Current Knowledge and Biotechnological Opportunities

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