Protein Engineering of the Progesterone Hydroxylating P450-Monooxygenase CYP17A1 Alters Its Regioselectivity-Reference-Cited by-同舟云学术

Protein Engineering of the Progesterone Hydroxylating P450-Monooxygenase CYP17A1 Alters Its Regioselectivity

Published:2018-08-07 Issue:18 Volume:19 Page:1954-1958
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Morlock Lisa K.¹,Grobe Sascha¹,Balke Kathleen¹,Mauersberger Stephan²,Böttcher Dominique¹,Bornscheuer Uwe T.¹^ORCID

Affiliation:

1. Department of Biotechnology and Enzyme Catalysis; Institute of Biochemistry; Greifswald University; Felix-Hausdorff-Strasse 4 17487 Greifswald Germany

2. Institute of Microbiology; Faculty of Biology; Dresden University of Technology; Zellescher Weg 20b 01062 Dresden Germany

Funder

Deutsche Forschungsgemeinschaft

TBI Mecklenburg-Vorpommern

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cbic.201800371/fullpdf

Reference26 articles.

1. Cytochrome P450 systems—biological variations of electron transport chains

2. Cytochrome P450: taming a wild type enzyme

3. Microbial P450 enzymes in biotechnology

4. Heme-iron oxygenases: powerful industrial biocatalysts?

5. Towards Preparative Scale Steroid Hydroxylation with Cytochrome P450 Monooxygenase CYP106A2

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