Affiliation:
1. Department of Surgery, Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
Abstract
Abstract
A total of 485 patients with a proven or suspected diagnosis of soft tissue sarcoma were referred over a 3-year period. Of these, 61 were referred for opinion only and 424 for definitive treatment. Overall there were 223 patients with primary soft tissue sarcoma and 84 with recurrent sarcoma, 84 with benign soft tissue tumours and 22 with non-soft tissue sarcoma malignancy; 11 patients were referred with known metastatic disease. The commonest benign tumours mimicking soft tissue sarcoma were fibromatosis and benign intermuscular or intramuscular lipoma. The malignant tumours suspected clinically of being soft tissue sarcoma were bone tumours, lymphoma and metastatic carcinoma. Of the 172 patients with primary soft tissue sarcoma referred with a proven diagnosis this had been established by excision biopsy in 94 and open incision biopsy in 48. By contrast, of those undiagnosed at referral, 44 of 51 patients with soft tissue sarcoma had the diagnosis made by Tru-cut core biopsy. Amputation was performed in four of 165 patients with primary extremity soft tissue sarcoma and in five of 54 with recurrent extremity sarcoma, giving an overall amputation rate of 4 per cent. It is proposed that the amputation rate for extremity soft tissue sarcoma can be reduced by the use of reconstructive procedures, particularly myocutaneous flaps to the proximal limbs and limb girdles, and free vascularized flaps to sites distal to the midthigh and midarm.
Publisher
Oxford University Press (OUP)
Reference27 articles.
1. Third National Cancer Survey. Incidence data;Cutler;National Cancer Institute Monograph,1984
2. The diagnosis of soft tissue tumours;Serpell;Ann R Coll Surg Engl,1992
3. Management of soft tissue sarcomas of the extremity;Shiu;Semin Oncol,1981
4. Anatomic extent of soft tissue sarcomas of the extremities: implications for surgical strategy;Monson;Proceedings of the Annual Meeting of the American Society of Clinical Oncology,1990
5. Limb-sparing surgery without radiotherapy based on anatomic location of soft tissue sarcoma;Rydholm;J Clin Oncol,1991
Cited by
47 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献