Cure of intractable watery diarrhoea by excision of a vipoma-Reference-Cited by-同舟云学术

Cure of intractable watery diarrhoea by excision of a vipoma

Published:1978-04 Issue:4 Volume:65 Page:234-236
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Modlin Irvin M¹,Bloom Stephen R¹,Barnes A¹,Welbourn R B¹

Affiliation:

1. Departments of Surgery and Medicine, Royal Postgraduate Medical School and Hammersmith Hospital, London

Abstract

Abstract A 56-year-old man suffered unexplained watery diarrhoea for 5 years which ultimately produced quadraparesis due to serve potassium depletion. All investigations were negative until demonstration of elevated plasma vasoactive intestinal peptide (VIP) indicated the presence of a vipoma. Removal of the VIP-producing tumour tissue–an adrenal ganglioneuroma–resulted in complete cure. Plasma VIP measurement is thus a valuable diagnostic screen in such cases and can be used to predict prognosis and to guide further therapy.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/65/4/234/37051431/bjs1800650406.pdf

Reference10 articles.

1. VIP measurement in distinguishing Verner-Morrison syndrome and pseudo Verner-Morrison syndrome;Bloom;Clin. Endocrinol.,1976

2. Vasoactive intestinal peptide and the watery diarrhoea syndrome;Bloom;Lancet,1973

3. Dual role for vasoactive intestinal peptide as a gastrointestinal hormone and neurotransmitter substance;Bryant;Lancet,1976

4. Streptozotocin treated Verner-Morrison syndrome;Gagel;Arch. Intern. Med.,1976

5. Recognition and management of the diarrhoeal syndrome caused by non-beta islet cell tumours of the pancreas;Kraft;Am. J. Surg.,1970

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