Plasma fatty acid profiles in benign breast disorders

Author:

Gateley C A1,Maddox P R1,Pritchard G A1,Sheridan W1,Harrison B J1,Pye J K1,Webster D J T1,Hughes L E1,Mansel R E1

Affiliation:

1. University Department of Surgery, University of Wales College of Medicine, Cardiff CF4 4XN, UK

Abstract

Abstract Breast pain (mastalgia) and macroscopic breast cysts present commonly. Mastalgia may be improved by dietary manipulation to reduce saturated fat or supplement essential fatty acid intake. Fatty acid profiles were measured in women with mastalgia and breast cysts, before and during treatment with evening primrose oil, a rich source of essential fatty acids. The fatty acid profiles of both groups of patients were abnormal, with increased proportions of saturated fatty acids and reduced proportions of essential fatty acids. Treatment with evening primrose oil improved the fatty acid profiles towards normal, but this was not necessarily associated with a clinical response.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference16 articles.

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2. The epidemiology of benign breast disease;Ernster;Epidemiol Rev,1981

3. Epidemiology and endocrinology of benign breast disease;Wang;Breast Cancer Res Treat,1985

4. Effect of a low-fat high-carbohydrate diet on symptoms of cyclical mastopathy;Boyd;Lancet,1988

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