Colloid osmotic pressure and serum albumin following surgery

Author:

Moore P J1,Clark R G1

Affiliation:

1. University Surgical Unit, Clinical Sciences Centre, Northern General Hospital, Sheffield S5 7AU

Abstract

Abstract The fall in serum albumin which occurs after operation can be modified by an intraoperative infusion of 20 g salt-poor human albumin, and the associated fall in colloid osmotic pressure is also corrected. There is a decrease in postoperative oliguria following a colloid infusion but no significant effect has been demonstrated on urinary sodium excretion. The alteration of fluid and electrolyte metabolism after surgery does not appear to be a direct effect of lowered plasma colloid osmotic pressure. It is suggested that the effect of intraoperative albumin infusion is predominantly haemo-dynamic.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference24 articles.

1. The internal balance of plasma proteins in surgical patients;Ariel;Surg. Gynecol. Obstet.,1951

2. Concentrations of serum proteins during and immediately after surgical trauma;Wandall;Acta Chir. Scand.,1974

3. Serum colloid osmotic pressure in the development of kwashiorkor and in recovery: its relationship to albumin and globulin concentrations and oedema;Coward;Br. J. Nutr.,1975

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