Prospective randomized multicentre trial of proximal gastric vagotomy or truncal vagotomy and antrectomy for chronic duodenal ulcer: Results after 5–7 years

Author:

de Vries B C12,Schattenkerk M Eeftinck12,Smith E E J12,Spencer J12,Jackson D S12,Alexander-Williams J12,Dorricott N J12

Affiliation:

1. University Hospital, Rotterdam ‘Dijkzigt’, Hammersmith Hospital, London

2. General Hospital, Birmingham

Abstract

Abstract In a prospective, randomized study 145 patients with duodenal ulcer have been followed 5–7 years after proximal gastric vagotomy (PGV) or truncal vagotomy with antrectomy (TVA). Postoperative complications were significantly higher after TVA (P < 0.0005). There was one death due to anastomotic leakage after TVA. The recurrence rate was significantly higher after PGV (9.9 per cent). Postoperative symptoms were less after PGV (P < 0.01). Due to the recurrence rate after PGV there was no overall significant difference in the Visick grading, although perfect results (Visick I) were seen significantly more often (P < 0.01) after PGV. It is concluded that better results follow PGV.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference23 articles.

1. Prospective randomized multicentre trial of proximal gastric vagotomy or truncal vagotomy and antrectomy for chronic duodenal ulcer: interim results;Dorricot;Br. J. Surg.,1978

2. Five to nine years results of selective proximal vagotomy with and without pyloroplasty for duodenal ulcer;Klas;Acta Chir. Scand.,1979

3. Proximal gastric vagotomy without drainage for duodenal ulcer: results after 5–8 years;Goligher;Br. J. Surg.,1978

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