The buerger syndrome in java. A description of the clinical syndrome and some aspects of its aetiology

Abstract

Abstract A case control field survey was carried out on 106 Indonesian patients with spontaneous peripheral gangrene. In 101 patients the disease was a four-limb youthful type of peripheral vascular disease occurring in young male smokers. Migratory superficial thrombophlebitis was present in 38 patients. This constellation of signs and symptoms was similar to that described for the Buerger syndrome. Of the aetiological factors studied, tobacco, cold injury, familial aggregation, and a past history of mycotic infection may be of significance.