Prostaglandin E1 in severe lower limb ischaemia: A double-blind controlled trial-Reference-Cited by-同舟云学术

Prostaglandin E1 in severe lower limb ischaemia: A double-blind controlled trial

Published:1984-07 Issue:7 Volume:71 Page:506-508
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Telles G S¹²,Campbell W B¹²,Wood R F M¹²,Collin J¹²,Baird R N¹²,Morris P J¹²

Affiliation:

1. Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK

2. Department of Surgery, Bristol Royal Infirmary, Bristol BS2 8HW, UK

Abstract

Abstract Thirty patients with ischaemic ulceration or rest pain due to lower limb atherosclerosis were treated with intravenous prostaglandin E1 (PGE1) or placebo in a prospective double-blind controlled trial. There was no significant improvement of rest pain, nor was PGE1 effective in promoting ulcer healing. This study provides no support for the use of intravenous PGE1 in the treatment of end-stage lower limb atherosclerotic disease.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/71/7/506/36929963/bjs1800710710.pdf

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