The treatment of advanced bladder cancer with sensitized pig lymphocytes

Author:

Feneley R C L1,Eckert H1,Riddell A G1,Symes M O1,Tribe C R1

Affiliation:

1. Departments of Surgery, Radiotherapy and Pathology, University of Bristol

Abstract

Abstract Twenty-five patients with transitional cell carcinoma of the urinary bladder have been treated by infusion of sensitized pig lymph node cells into the arterial blood supply of the tumour. In 7 cases pig cell infusion was the only treatment, in a further 7 patients pig cells were given in the treatment of a major tumour recurrence following radiotherapy and in 11 patients pig cell infusion was followed after 4-8 weeks by an attenuated course of radiotherapy. In these three treatment groups 2, 3 and 9 patients respectively obtained clinical benefit and biopsy showed histological change.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference4 articles.

1. Immunologically specific activation of macrophages armed with the specific macrophage arming factor;Evans;Proc. Soc. Exp. Biol. Med.,1973

2. The Bristol Bladder Tumour Registry;Miller;Br. J. Urol. Suppl.,1969

3. The use of immunized pig lymph node cells in the treatment of patients with advanced malignant disease;Symes;Br. J. Surg.,1973

4. The treatment of advanced bladder cancer with sensitised pig lymphocytes;Symes;Br. J. Concer,1973

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