Preclinical warning of recrudescent mammary cancers by pregnancy-associated alpha-macroglobulin-Reference-Cited by-同舟云学术

Preclinical warning of recrudescent mammary cancers by pregnancy-associated alpha-macroglobulin

Published:1976-10 Issue:10 Volume:63 Page:819-822
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Anderson J Maxwell¹,Stimson W H²,Kelly F³

Affiliation:

1. Surgical Division, Royal Infirmary, Glasgow

2. Department of Biochemistry, University of Strathclyde, Glasgow

3. Glasgow Institute of Radiotherapeutics

Abstract

Abstract Nine of 30 mammary cancer patients developed metastases during 13–94 months after mastectomy. All 9 patients had elevated blood levels of pregnancy-associated α-macroglobulin (PAM) 1–21 months before conventional detection of metastases. Seven of the clinically well patients had PAM rises exceeding 90 per cent above the baseline and in 4 of these the PAM later fell to lower levels. PAM appears to have potential as an indicator of the growth of micrometastases.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/63/10/819/37054794/bjs1800631022.pdf

Reference14 articles.

1. Serum glycoprotein level at different stages of tumour growth;Abdel-Ghaffar;Br. J. Cancer,1967

2. Study of serum glycoproteins in cancer;Almquist;Scand. J. Clin. Lab. Invest.,1957

3. Immunological inertia in pregnancy;Anderson;Nature (Lond.),1965

4. Stimulatory immunotherapy in mammary cancer;Anderson;Br. J. Surg.,1974

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Serum levels of six tumor markers in patients with benign and malignant gynecological disease;Archives of Gynecology and Obstetrics;1988

2. Pregnancy-associated alpha2 glycoprotein (α2PAG) synthesis by human breast cancer tissue and cultured cell lines;International Journal of Cancer;1983-02-15

3. Limitations of using pregnancy-associated alpha-2 glycoprotein as a tumour marker;European Journal of Cancer and Clinical Oncology;1982-04

4. The pregnancy-associated ?2-glycoprotein (?2-PAG) A tumour marker?;Klinische Wochenschrift;1981-02

5. Plasma Concentrations of Pregnancy-Associated Alpha-2-Glycoprotein in Patients with Leukaemia;Acta Haematologica;1981