Peritoneal dialysis in obstructive jaundice: An experimental study

Author:

Kaushik S P1,Subrahmanyam M1,Kumar M1,Chakravarty R N1

Affiliation:

1. Department of Surgery and Experimental Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India

Abstract

Abstract Rats were subjected to common bile duct ligation, after which intermittent peritoneal dialysis with a buffered solution containing rat plasma proteins was carried out in an attempt to reduce plasma bilirubin levels. Plasma bilirubin increased significantly (P <0.01) on the seventh day and was still rising 12 days after ligation of the common bile duct. Dialysis was performed during the second postoperative week. Provided that rat plasma protein was present in the dialysing fluid, dialysis significantly reduced (P <0.01) the levels of total plasma bilirubin, conjugated bilirubin and serum GPT in the experimental animals.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference12 articles.

1. The incidence of postoperative renal failure in obstructive jaundice;Dawson;Br. J. Surg,1965

2. Recent advances in jaundice: surgical aspects;Dawson;Br. Med. J.,1970

3. Intermittent peritoneal dialysis in treatment of experimental salicylate intoxication;Ettledorf;J. Pediatr.,1960

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