Evaluation of breast tumour sex chromatin (barr body) as an index of survival and response to pituitary ablation

Abstract

Abstract In a retrospective study of 36 patients with advanced oreast cancer relationships were found between the cumour Barr body count and the response to pituitary ablation and the length of survival. High tumour Barr body counts were associated with long survival after treatment, and low counts with short survival. (P < 0.001). High counts were also associated with a good response to pituitary ablation, and low counts with a poor response (P < 0.01). The tumour Barr body count gave possibly better prediction than urinary steroid measurement.