Decreased incidence of indomethacin-induced gastric ulceration in rats by bile duct diversion-Reference-Cited by-同舟云学术

Decreased incidence of indomethacin-induced gastric ulceration in rats by bile duct diversion

Published:1975-02 Issue:2 Volume:62 Page:113-114
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Abtahi Foroogh S¹,Djahanguiri Bijan¹

Affiliation:

1. Department of Pharmacology, Faculty of Medicine, University of Tehran, Iran

Abstract

Abstract Gastric mucosal ulceration was produced in rats following intraperitoneal injection of indomethacin (40 mg/kg). The incidence of ulcerations was progressively reduced as the bile flow was diverted progressively distal to the ampulla of Vater. It is suggested that bile reflux into the stomach may play a part in the pathogenesis of indomethacin-induced gastric ulceration in rats.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/62/2/113/37076998/bjs1800620208.pdf

Reference12 articles.

1. A test for pyloric regurgitation;Capper;Lancet,1966

2. The production of acute gastric ulceration by indomethacin in the rat;Djahanguiri;Scand. J. Gastroenterol.,1969

3. Prevention of aspirin-induced gastric ulceration by bile duct or pylorus ligation in the rat;Djahanguiri;Gastroenterology,1973

4. Gastric blood flow and its distribution during indomethacin administration;Edlich;Surg. Gynecol. Obstet.,1970

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. How to mechanistically explain the CONDOR study data;Medical Hypotheses;2015-01

2. Mast Cells Are Critical for Protection against Peptic Ulcers Induced by the NSAID Piroxicam;PLoS ONE;2011-08-12

3. Intestinal mucosal damage caused by non-steroidal anti-inflammatory drugs: Role of bile salts;Clinical Biochemistry;2007-05

4. Antiinflammatory and gastrointestinal effects of nabumetone or its active metabolite, 6-methoxy-2-naphthylacetic acid (6MNA);Digestive Diseases and Sciences;1992-12

5. Comparison of the effects of nabumetone with indomethacin on rat gastric mucosal 6-keto-PGF1α production and on bile salt-induced changes in gastric mucosal function;Journal of Pharmacy and Pharmacology;1987-09