HLA antigens in relationship to duodenal ulceration, gastric acid secretion and the clinical result following vagotomy-Reference-Cited by-同舟云学术

HLA antigens in relationship to duodenal ulceration, gastric acid secretion and the clinical result following vagotomy

Published:1982-02 Issue:2 Volume:69 Page:105-107
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Gough M J¹²,Rajah S M¹²,Giles G R¹²

Affiliation:

1. University Department of Surgery, St James's University Hospital, Leeds

2. Regional Blood Transfusion Centre, Leeds

Abstract

Abstract The distribution of 20 HLA antigens was measured in 100 patients with a duodenal ulcer. An increase (P < 0·05) in the incidence of the HLA-BW35 antigen was identified which conferred an increased risk factor of developing a duodenal ulcer of 2·7. The preoperative acid output in patients who had the BW35 antigen was significantly lower than that found in all other patients prior to surgery. The clinical outcome from definitive surgical treatment did not appear to be influenced by the HLA status of the patients.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/69/2/105/36938179/bjs1800690216.pdf

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