The role of the pyloric antrum and Hofmeister valve in the development of the chronic gastric mucosal reaction

Author:

Lawson H H1

Affiliation:

1. Department of Surgery, University of the Witwatersrand, and Baragwanath Hospital, Johannesburg, South Africa

Abstract

Abstract A limited chronic gastric mucosal reuction (CGMR) develops when duodenal contents enter the stomach with an intact pyloric antrum. However, after antrectomy the same stimulus leads to a widespread CGMR. The pyloric antrum, therefore, seems to influence the development of the CGMR. A Hofmeister valve included in a Polya gastrectomy does not prevent the development of the CGMR, presumably because reflux is not prevented.

Funder

South African Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Surgery

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4. Reflux gastritis following gastric surgery;Drapanas;Ann. Surg.,1974

5. The importance of the pyloric antrum in peptic ulceration;Du Plessis;S. Afr. J. Surg.,1963

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