A prolonged course of cyclophosphamide as an adjunct to mastectomy in the primary treatment of breast carcinoma-Reference-Cited by-同舟云学术

A prolonged course of cyclophosphamide as an adjunct to mastectomy in the primary treatment of breast carcinoma

Published:1976-10 Issue:10 Volume:63 Page:817-818
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Donovan I A¹²,Powell Jean¹²,Waterhouse J A H¹²,Morrissey D M¹²

Affiliation:

1. Queen Elizabeth Hospital, Birmingham

2. The Birmingham Regional Cancer Registry

Abstract

Abstract Cyclophosphamide given after mastectomy for 4–6 months to a consecutive series of patients seen in one surgical practice in the years 1964 and 1965 significantly improved the 10-year survival rate of the treated patients as compared with the patients seen consecutively in the same surgical practice in the years 1957–63. Staging showed that the improvement was due to a significant increase in the survival rate in patients with histologically negative axillary nodes (P < 0·01). There was no significant difference in survival in the node positive or advanced disease groups.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/63/10/817/37054796/bjs1800631021.pdf

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