Prospective randomized trial of mechanical bowel preparation in patients undergoing elective colorectal surgery-Reference-Cited by-同舟云学术

Prospective randomized trial of mechanical bowel preparation in patients undergoing elective colorectal surgery

Published:1994-11 Issue:11 Volume:81 Page:1673-1676
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Santos J C M¹,Batista J¹,Sirimarco M T¹,Guimarães A S¹,Levy C E²

Affiliation:

1. Section of Proctology, Department of Surgery, Orthopaedics and Traumatology, Medical School of Ribeirão Preto, Brazil

2. Laboratory of Microbiology, University Hospital, Medical School of Ribeirão Preto, Brazil

Abstract

Abstract A total of 149 patients admitted for elective colorectal surgery were randomly allocated to receive preoperative mechanical bowel preparation (group 1) or no mechanical bowel preparation (group 2). All patients received antimicrobial prophylaxis with cephalothin and metronidazole. The overall incidence of wound infection was 17·4 per cent (24 per cent for group 1, 12 per cent for group 2) and that of dehiscence 7·4 per cent (10 per cent for group 1, 5 per cent for group 2). The incidence of wound infection was significantly higher in group 1 (P<0·05) but that of anastomotic dehiscence did not differ significantly between groups. Mechanical bowel preparation is unnecessary and may be harmful in terms of preventing wound infection and anastomotic dehiscence in patients undergoing elective colorectal surgery.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/81/11/1673/36823161/bjs1800811139.pdf

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