Report of a family with inherited medullary carcinoma of the thyroid and phaeochromocytoma

Author:

Beaugie J M1,Belchetz P E1,Brown C L1,Frankel R J1,Lloyd Margaret H1

Affiliation:

1. Departments of Medicine and Surgery, and the Institute of Pathology, The London Hospital, London

Abstract

Abstract A family in which several members have medullary carcinoma and phaeochromocytoma is described. Four of the 5 patients in this family who had a phaeochromocytoma have died; in one of these the medullary carcinoma may have contributed to death but in general the thyroid cancers were slow growing. In our experience successful diagnosis and treatment of the phaeochromocytomas have presented the greatest challenge. The welfare of future generations with this syndrome would seem to depend upon regular clinical and biochemical surveillance of the individuals and expeditious diagnosis and treatment of their tumours, particularly the phaeochromocytomas.

Publisher

Oxford University Press (OUP)

Subject

Surgery

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4. Treatment of phaeochromocytoma—diagnosis and preparation for operation;Dequattro;Calif. Med.,1972

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