A circulating depressant effect following canine haemorrhagic shock-Reference-Cited by-同舟云学术

A circulating depressant effect following canine haemorrhagic shock

Published:1973-05 Issue:5 Volume:60 Page:392-394
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Fisher W D¹²,Heimbach D W¹²,McArdle C S¹²,Maddern M¹²,Hutcheson Maureen M¹²,Ledingham I McA¹²

Affiliation:

1. University Department of Surgery, Western Infirmary, Glasgow

2. Department of Pharmacology, University of Strathclyde, Glasgow

Abstract

Abstract Following periods of 1 or 3 1/2 hours of haemorrhagic shock in 12 anaesthetized ventilated greyhounds, ultrafiltrates of plasma taken 4 hours after retransfusion exibited significantly increased depressant activity on guinea-pig atrium in vitro. This effect was significantly greater following prolonged hypotension and could not be accounted for by changes in electrolyte composition. It is suggested that this effect may be related to defective myocardial function following haemorrhagic shock.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

http://academic.oup.com/bjs/article-pdf/60/5/392/37079729/bjs1800600521.pdf

Reference12 articles.

1. FURTHER CHARACTERIZATION OF A MYOCARUIAL DEPRESSANT FACTOR PRESENT IN HEMORRHAGIC SHOCK

2. Myocardial Depressant Factor in Plasma from Cats in Irreversible Post-Oligemic Shock.

3. Functional Cardiac Deterioration During Development of Hemorrhagic Circulatory Deficiency

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