Allergic starch peritonitis in the guinea-pig

Author:

Grant J B F1,Davies J D1,Jones J V1

Affiliation:

1. Departments of Surgery, Pathology and Medicine, University of Bristol

Abstract

Abstract An experimental starch peritonitis in guinea-pigs previously immunized with starch glove powder and Freund's complete adjuvant is described. After peritoneal challenge by 10 mg starch glove powder, 22 per cent of the animals developed florid omental granulomas resembling those found in some patients with postoperative glove powder peritonitis. It is suggested that delayed hyper sensitivity to a component of the glove powder may be responsible for the clinical features of starch peritonitis in man.

Funder

United Bristol Hospitals Research Committee

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference13 articles.

1. Granulomatous peritonitis secondary to corn starch;Bates;Ann. Intern. Med.,1965

2. Starch granuloma (pseudo-malignant seedlings);Cox;Br. J. Surg.,1970

3. Granulomatous hypersensitivity;Epstein;Prog. Allergy,1967

4. Starch dermatitis: evidence of immunogenicity of surgical glove powder in the guinea-pig;Grant;Br. J. Exp. Pathol.,1975

5. The starch-peritoneal reaction: an experimental study;Hartmann;Ann. Surg.,1972

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