Intussusception due to inflammatory fibroid polyps of the ileum: A report of 12 cases from Africa

Author:

Nkanza N K1,King M2,Hutt M S R1

Affiliation:

1. Geographical Pathology Unit, Department of Morbid Anatomy, St Thomas's Hospital Medical School, London

2. Queen Elizabeth Central Hospital, Blantyre, Malawi

Abstract

Summary Eleven cases of inflammatory fibroid polyp of the ileum from Malawi and 1 from Sierra Leone are described. All 12 patients presented with acute intestinal obstruction as a result of an intussusception caused by the polyp. The lesions are characterized by a variable proliferation of fibroblasts and small vessels which may involve the whole thickness of the bowel wall. Tissue mast cells and eosinophils were noted in all the polyps. The aetiology of these lesions remains obscure but they appear to be reactive rather than neoplastic. The condition appears to occur more commonly in Malawi than in the United Kingdom or North America and is an important cause of small bowel obstruction in that part of Africa.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference11 articles.

1. Inflammatory fibroid polyp of the gastrointestinal tract;Johnstone;Histopathology,1978

2. Inflammatory fibroid polyps of the ileum and caecum;McGee;Arch. Pathol.,1960

3. Inflammatory fibroid polyps of the gastrointestinal tract;Samter;Am. J. Clin. Pathol.,1966

4. Gastric submucosal granuloma with eosinophilic infiltration;Vanek;Am. J. Pathol.,1949

5. Recurrent eosinophilic infiltrate (granuloma) of the ileum causing intussusception in a 2-year-old child;McGreevy;Surgery,1967

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