Experimental autotransplantation of the parathyroid gland

Author:

Prigouris S1,Lorentziadis M1,Stylogiannis S1,Nafas R1,Masouras A1,Poulantzas I1

Affiliation:

1. Fourth Department of Surgery, ‘Evangelismos’ Hospital, Athens, Greece

Abstract

Abstract The lateral parathyroid gland of the rabbit was resected and autotransplanted under an ear skin flap. A skin flap at the opposite side was used as control. The success of autotransplantation was established by microangiography of the transplant and by measuring plasma concentrations of parathyroid hormone (PTH), calcium and phosphorus. After 4 months the animals were killed and the transplant was studied histologically and by electron microscopy. Fourteen animals were included in the study. There was an increase in PTH derived from the transplanted gland after 4–6 postoperative days. All animals developed hypocalcaemia during the 3 days after transplantation. There were no significant changes in serum phosphorus. Transplantation did not alter the morphology of the distribution of the cells in the transplanted gland, which functioned normally after the fourth postoperative day.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference18 articles.

1. Minimizing hypoparathyroidism after extended thyroid operations;Block;Surg Gynecol Obstet,1966

2. Hypoparathyroidism following total thyroidectomy in 201 thyroid cancer patients. Incidence, management and complications;Rose,1963

3. Post-thyroidectomy hypoparathyroidism;Hans;Am Surg,1976

4. Thyroid carcinoma in children;Anderson;Am Surg,1977

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